{"product_id":"9780128239322","title":"Epigenetics in Organ Specific Disorders","description":"**Selected for Doody's Core Titles® 2024 in Clinical Genetics**Epigenetics in Organ Specific Disorders, a new volume in the Translational Epigenetics series, provides a foundational overview and nuanced analysis of epigenetic gene regulation distinct to each organ type and organ specific disorders, fully elucidating the epigenetics pathways that promote and regulate disease. After a brief introduction, chapter authors compare epigenetic regulations across normal and disease conditions in different organ tissues, exploring similarities and contrasts. The role of epigenetic mechanisms in stem cells, cell-matrix interactions and cell proliferation, cell migration, cellular apoptosis, necrosis, pyknosis, tumor suppression, and immune responses across different organ types are examined in-depth.Organ specific epigenetic mechanisms and biomarkers of early use in developing drugs, which can selectively target the organ of interest, are also explored to enable new precision therapies.\u003cp\u003e\u003c\/p\u003e- Identifies unique epigenetic mechanisms that occur in normal and disease conditions in each organ, examining differences and similarities\u003cp\u003e\u003c\/p\u003e- Explores organ specific epigenetic mechanisms to enable drug discovery and development\u003cp\u003e\u003c\/p\u003e- Features chapter contributions from leading researchers in the field","brand":"Elsevier Science \u0026 Technology Books","offers":[{"title":"Default Title","offer_id":46588996681969,"sku":"9780128239322","price":175.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0674\/5433\/7265\/files\/9780128239322_p0.jpg?v=1765841930","url":"https:\/\/shop.barnesandnoble.com\/products\/9780128239322","provider":"Barnes \u0026 Noble","version":"1.0","type":"link"}