{"product_id":"9789811374494","title":"Actin Polymerization in Apicomplexan: A Structural, Functional and Evolutionary Analysis","description":"This book discusses in detail the structural, evolutionary and functional role of actin and its regulatory proteins in gliding motility in apicomplexan organisms, a unique phenomenon found in actin-myosin cytoskeletal elements.    \u003cp\u003e The book also explores the potential of different actin regulators, namely formin, profilin, actin depolymerization factor (ADF), capping proteins (CPα and CPβ), cyclase-associated protein (CAP) and coronin 13–24 as potential drug targets against malaria. As the chief components of the gliding motor, the actin-regulator proteins are characterized by unique features that make them promising targets for structure-based drug design. \u003c\/p\u003e   \u003cp\u003e Lastly, the book proposes a mathematical model, based on kinetic data mining, to help understand the most vital regulators for actin polymerization dynamics.  \u003c\/p\u003e","brand":"Springer Nature Singapore","offers":[{"title":"Default Title","offer_id":46312705753329,"sku":"9789811374494","price":109.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0674\/5433\/7265\/files\/9789811374494_p0.jpg?v=1765019485","url":"https:\/\/shop.barnesandnoble.com\/products\/9789811374494","provider":"Barnes \u0026 Noble","version":"1.0","type":"link"}